EpiGuide® is a uniquely structured bioresorbable polyactide (PLA) membrane designed to be used in many applications within guided tissue regeneration (GTR) and guided bone regeneration (GBR) procedures.
The patented barrier matrix is characterized by its unique three-dimensional architecture. The innovative structure is easily recognizable in the cross section: The inner layer, featuring large and closed pores, transforms into a chamber-like structure in the intermediate layer and then into the highly porous outer layer, also featuring large pores.
The patented barrier matrix is characterized by its unique three-dimensional architecture. The innovative structure is easily recognizable in the cross section: The inner layer, featuring large and closed pores, transforms into a chamber-like structure in the intermediate layer and then into the highly porous outer layer, also featuring large pores.
- Layer 1: Gingival Interface
Numerous voids and intercommunicating pathways enhance fibroblast infiltration and cell attachment. - Layer 2: Inner Surface
Inner labyrinth creates pathways, while internal chambers enable collateral circulation and flow of intersititial fluid in the membrane. - Layer 3: Defect Interface
Optical porosity supports the uptake of fluid, helps adherence to the tooth surface, and inhibits fibroblast movement.
The structure and integrity of EpiGuide are maintained for more than six weeks after implantation. Full resorption is completed within six to twelve months.